. 2016 Nov 4;16:438. doi: 10.1186/s12906-016-1422-4

Table 6.

The effect of treating CCl4 induced hepatotoxicity in male rats with olive oil and N. sativa oil for 4 weeks on liver enzymes, total proteins, albumin and total bilirubin

Liver enzymes U/l	Statistics	G1	G2	G3	G4
Liver enzymes U/l	Statistics	N. Control	P. Control	Olive oil	Nigella sativa oil
AIT	Mean ± SE	25.16 ± 1.35^d	71.00 ± 1.41^a	58.83 ± 0.47^b	52.16 ± 1.13^c
	LSD0.05 = 3.275	25.16 ± 1.35^d	71.00 ± 1.41^a	58.83 ± 0.47^b	52.16 ± 1.13^c
	T-test	-	−21.00***	7.15***	39.46***
AST	Mean ± SE	26.50 ± 0.76^d	81.16 ± 1.66^a	65.50 ± 0.99^b	50.50 ± 1.11^c
	LSD0.05 = 2.501	26.50 ± 0.76^d	81.16 ± 1.66^a	65.50 ± 0.99^b	50.50 ± 1.11^c
	T-test	-	−44.47***	10.95***	23.91***
ALP	Mean ± SE	156.66 ± 2.17^d	286.16 ± 2.82^a	228.50 ± 2.50^b	185.50 ± 2.43^c
	LSD 0.05 = 8.122	156.66 ± 2.17^d	286.16 ± 2.82^a	228.50 ± 2.50^b	185.50 ± 2.43^c
	T-test	-	−37.51***	14.90***	19.55***
Total protein	Mean ± SE	7.65 ± 0.04^a	4.81 ± 0.09^d	5.66 ± 0.04^c	6.80 ± 0.05^b
	LSD 0.05 = 0.201	7.65 ± 0.04^a	4.81 ± 0.09^d	5.66 ± 0.04^c	6.80 ± 0.05^b
	T-test	-	22.55***	−10.04***	−16.22***
Albumin	Mean ± SE	4.50 ± 0.05^a	2.56 ± 0.09^d	3.10 ± 0.04^c	3.85 ± 0.04^b
	LSD 0.05 = 0.203	4.50 ± 0.05^a	2.56 ± 0.09^d	3.10 ± 0.04^c	3.85 ± 0.04^b
	T-test	-	15.72***	−4.78***	−16.19***
Total Bilirubin mg/dl	Mean ± SE	0.42 ± 0.00^d	1.38 ± 0.03^a	0.84 ± 0.00^b	0.76 ± 0.04^c
	LSD 0.05 = 0.077	0.42 ± 0.00^d	1.38 ± 0.03^a	0.84 ± 0.00^b	0.76 ± 0.04^c
	T-test	-	−28.02***	15.58***	15.11***

Data are represented as mean ± SE. T-test values ***: significant at P < 0.001. ANOVA analysis: within each row, means with different superscript (a, b, c or d) are significantly different at P < 0.05, whereas means superscripts with the same letters mean that there is no significant difference at P > 0.05. LSD least significant difference