Table 2. Effect sizes for associations between prenatal famine exposure and cardiovascular measures in response to stress.
Exposure to famine during gestation | ||||||
---|---|---|---|---|---|---|
Late (B [95%CI]) | p-value | Mid (B [95%CI]) | p-value | Early (B [95%CI]) | p-value | |
SBP (mmHg) | 0.39 [-2.81 to 3.58] | 0.81 | -0.20 [-3.58 to 3.19] | 0.91 | 3.93 [-0.31 to 8.18] | 0.069 |
HR (bpm) | -0.01 [-1.12 to 1.10] | 0.99 | 0.44 [-0.76 to 1.65] | 0.47 | 0.17 [-1.34 to 1.68] | 0.82 |
LF-SBP (mmHg2) | -0.97 [-3.51 to 1.56] | 0.45 | -1.59 [-4.34 to 1.16] | 0.26 | -0.46 [-3.89 to 2.97] | 0.79 |
HF-HP (ms2) | -20.2 [-50.0 to 9.7] | 0.19 | 6.0 [-26.4 to 38.3] | 0.72 | 17.3 [-22.7 to 22.1] | 0.98 |
LF/HF ratio | 0.12 [-0.28 to 0.52] | 0.57 | -0.06 [-0.49 to 0.38] | 0.79 | 0.34 [-0.20 to 0.88] | 0.22 |
Data are given as B [95% confidence intervals] with p-value from repeated mixed measures analysis comparing mean stress reactivity profiles for those exposed to famine during gestation compared to those unexposed during gestation; models were adjusted for sex and baseline cardiovascular activity; CI = confidence interval; SBP = systolic blood pressure; HR = heart rate; LF = low frequency; HF = high frequency; HP = heart period.