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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Acta Biomater. 2016 Sep 27;46:221–233. doi: 10.1016/j.actbio.2016.09.026

Table 1.

Physical parameters of emulsions used to dope the acoustically responsive scaffolds

Number
Weighted Mean
Diameter (μm)
Volume Weighted
Mean Diameter
(μm)
Droplet
Concentration
(Number/mL)
ADV Threshold
(MPa)
Encapsulation
Efficiency (%)

Perfluorocarbon Distribution
Size
Payload Mean SEM Mean SEM Mean SEM Mean SEM Mean SEM
100%
Perfluoropentane
(C5)
Large AF680
Dextran
3.5 0.1 21.2 0.5 1.0E + 10 2.2E + 8 1.7 0.2 82.5 7.8
Small AF680
Dextran
3.0 0.1 11.8 0.2 7.4E + 10 8.2E + 8 1.9 0.1 50.1 9.9

1:1
Perfluoropentane:
Perfluorohexane
(C5C6)
Large AF680
Dextran
3.4 0.1 20.8 0.4 1.5E + 10 2.2E + 8 2.1 0.1 72.7 5.1
Small AF680
Dextran
2.9 0.1 10.7 0.1 1.1E + 11 6.6E + 8 2.3 0.1 67.4 3.7

100%
Perfluorohexane
(C6)
Large AF680
Dextran
3.5 0.1 21.5 0.9 2.3E + 10 2.1E + 9 2.5 0.1 75.9 2.0
Small AF680
Dextran/DPBS
2.8 0.1 10.6 0.1 1.0E + 11 6.3E + 8 2.7 0.1 70.0 8.6