Table 1.
Physical parameters of emulsions used to dope the acoustically responsive scaffolds
Number Weighted Mean Diameter (μm) |
Volume Weighted Mean Diameter (μm) |
Droplet Concentration (Number/mL) |
ADV Threshold (MPa) |
Encapsulation Efficiency (%) |
||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
|
||||||||||||
Perfluorocarbon | Distribution Size |
Payload | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM | Mean | SEM |
100% Perfluoropentane (C5) |
Large | AF680 Dextran |
3.5 | 0.1 | 21.2 | 0.5 | 1.0E + 10 | 2.2E + 8 | 1.7 | 0.2 | 82.5 | 7.8 |
Small | AF680 Dextran |
3.0 | 0.1 | 11.8 | 0.2 | 7.4E + 10 | 8.2E + 8 | 1.9 | 0.1 | 50.1 | 9.9 | |
| ||||||||||||
1:1 Perfluoropentane: Perfluorohexane (C5C6) |
Large | AF680 Dextran |
3.4 | 0.1 | 20.8 | 0.4 | 1.5E + 10 | 2.2E + 8 | 2.1 | 0.1 | 72.7 | 5.1 |
Small | AF680 Dextran |
2.9 | 0.1 | 10.7 | 0.1 | 1.1E + 11 | 6.6E + 8 | 2.3 | 0.1 | 67.4 | 3.7 | |
| ||||||||||||
100% Perfluorohexane (C6) |
Large | AF680 Dextran |
3.5 | 0.1 | 21.5 | 0.9 | 2.3E + 10 | 2.1E + 9 | 2.5 | 0.1 | 75.9 | 2.0 |
Small | AF680 Dextran/DPBS |
2.8 | 0.1 | 10.6 | 0.1 | 1.0E + 11 | 6.3E + 8 | 2.7 | 0.1 | 70.0 | 8.6 |