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. 2016 Sep 13;9(6):345–351. doi: 10.1007/s12328-016-0680-5

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 5 — Histologic and immunohistochemical features of the adenocarcinoma and non-neoplastic fundic glands. a H&E stained tissue. The border between GAFG and non-neoplastic oxyntic mucosa is evident. b Pepsinogen-I staining. The neoplastic glands are more weakly stained than the non-neoplastic fundic glands. c Staining for MIST-1. Many positively stained cells are evident in the neoplastic glands. d Staining for H⁺/K⁺-ATPase. Positively stained neoplastic cells are prominent in the upper portion of the mucosa. e Staining for MUC6. The distribution of positively stained neoplastic cells corresponds well with that of cells stained positively for MIST-1. f Ki-67 staining. Black bar 200 μm