Table 2.

Statistical Correlation of Clinical Variables to Histologic Subtypes in HNRMS

Clinical variables		Histologic subtype						P value (Fisher's exact)*
		ARMS (n = 33)		ERMS (n = 53)		SRMS-ScRMS (n = 13)
Gender								0.541
	Male	19	58%	25	47%	8	61%
	Female	14	42%	28	53%	5	39%
Age (years)	Mean	23		8.7		29		<0.001 (ANOVA)
	Median	23		6		28		<0.001 Kruskal-Wallis
	Max.	57		38		72
	Min.	0.08		0.3		0.7
Age group								<0.001
	Adult	22	67%	7	13%	8	61%
	Pediatric	11	33%	46	87%	5	39%
Tumor site								<0.001
	PM	28	85%	33	62%	3	23%
	S	4	12%	11	21%	10	77%
	O	1	3%	9	17%	0	0%
Tumor size	Mean	4		4		5		0.344 (ANOVA)
	Median	4		4		5		0.517 Kruskal-Wallis
	Max.	9		12		10
	Min.	1		1.3		0.8
Regional lymph node								<0.001
	Positive	24	72%	14	27%	2	17%
	Negative	9	28%	38	73%	10	83%
Initial metastasis								0.078
	Positive	10	30%	6	11%	3	23%
	Negative	23	70%	47	89%	10	77%
Stage								0.001
	1	4	12%	16	30%	9	69%
	2	2	6%	8	15%	0	0%
	3	17	52%	23	44%	1	8%
	4	10	30%	6	11%	3	23%
Recurrence								0.001
	LR	6	18%	3	6%	2	18%
	DR, (LR & DR)	8	24%	1	2%	2	18%
	NR	19	58%	49	92%	7	64%
Vital status								0.05
	Alive	20	61%	43	81%	6	54%
	Deceased	13	39%	10	19%	5	46%
Follow-up duration (months)	Mean	63		106		35		<0.001 (ANOVA)
	Median	32		104		29		<0.001 Kruskal-Wallis
	Max.	232		232		94
	Min.	4		7		4

PM – Parameningeal, S – Non parameningeal non orbital, O – Orbital, LR – Local recurrence, DR – Distant recurrence, NR – No recurrence

^*P values calculated with Fisher's exact if not otherwise specified