Table 1. Baseline Patient Characteristics.
| Total Patients N=428 | |||||
|---|---|---|---|---|---|
| Demographics | N (%) | Imaging characteristics | N (%) | ||
| Age (years) | <65 | 205 (48) | Ascites | Absent | 350 (82) |
| ≥65 | 223 (52) | Present | 78 (18) | ||
| Gender | Male | 312 (73) | Portal Hypertension | Present | 320 (75) |
| Female | 116 (27) | Absent | 108 (25) | ||
| Ethnic Group | Caucasian | 300 (70) | Infiltrative | Yes | 128 (30) |
| Asian | 41 (10) | No | 300 (70) | ||
| Hispanic | 29 (7) | Tumor Burden | 0-25% | 342 (80) | |
| African-American | 45 (10) | 26-50% | 66 (15) | ||
| Native-American | 2 (0) | >50% | 20 (5) | ||
| Unknown | 11 (3) | Lobar Distribution | Unilobar | 219 (51) | |
| Etiology | Alcohol | 76 (18) | Bilobar | 209 (49) | |
| Cryptogenic | 63 (15) | Tumor Focality | Solitary | 135 (31) | |
| HBV | 40 (9) | Multifocal | 293 (69) | ||
| HCV | 151 (35) | Largest Index Tumor Size (cm) | ≤5 cm | 194 (45) | |
| HCV + Alcohol | 26 (6) | 5.1-10 cm | 165 (39) | ||
| NASH | 18 (4) | >10 cm | 69 (16) | ||
| Primary Biliary Cirrhosis | 8 (2) | Portal Vein Thrombosis | Absent | 272 (64) | |
| Unknown | 26 (6) | Main | 84 (20) | ||
| Miscellaneous | 20 (5) | Lobar | 72 (16) | ||
| Method of Diagnosis | Biopsy | 201 (47) | Extrahepatic Disease | Absent | 377 (88) |
| Imaging | 227 (53) | Present | 51 (12) | ||
| Laboratory values | N (%) | Miscellaneous | N (%) | ||
| Alpha-fetoprotein (ng/mL) | ≤200 | 242 (57) | ECOG | 0 | 235 (55) |
| >200 | 186 (43) | 1 | 163 (38) | ||
| Bilirubin (mg/dL) | < 2 | 360 (84) | |||
| > 2 | 68 (16) | 2 | 30 (7) | ||
| Albumin (g/dL) | ≥ 2.8 | 230 (54) | |||
| < 2.8 | 198 (46) | Previous Liver Directed Therapy | No | 383 (89) | |
| Alkaline Phosphatase (U/L) | ≤ 200 | 349 (82) | |||
| >200 | 79 (18) | Yes | 45 (11) | ||