Table 3. Comparison of HCC Staging Systems.
Staging System | Discriminatory Ability Linear Trend X2 | Homogeneity Likelihood Ratio X2 Test | Akaike Information Criterion; P value of comparison of CLIP to Model | Discrimination for Model Validation Cindex |
---|---|---|---|---|
All patients censored to transplantation (N=428) | ||||
CLIP | 118.18 | 127.22 | 2992.80; N/A | 0.8503 |
JIS Score | 101.37 | 103.98 | 3014.04; <0.0001 | 0.8474 |
UNOS | 93.14 | 94.61 | 3023.41; <0.0001 | 0.8393 |
BCLC | 79.49 | 81.97 | 3032.05; <0.0001 | 0.7749 |
GRETCH | 72.98 | 73.40 | 3038.61; <0.0001 | 0.7726 |
CUPI | 56.20 | 64.45 | 3047.57; <0.0001 | 0.7037 |
Okuda | 48.99 | 53.13 | 3058.89; <0.0001 | 0.6889 |
CTP | 35.69 | 38.00 | 3074.02; <0.0001 | 0.6445 |
All patients with intention to treat survival (N=428) | ||||
CLIP | 154.91 | 164.43 | 3057.86; N/A | 0.8157 |
UNOS | 136.97 | 156.90 | 3073.79; <0.0001 | 0.7885 |
JIS Score | 130.20 | 143.95 | 3080.56; <0.0001 | 0.7822 |
BCLC | 118.78 | 133.89 | 3087.99; <0.0001 | 0.7761 |
GRETCH | 95.41 | 111.55 | 3109.36; <0.0001 | 0.6927 |
CUPI | 71.06 | 71.92 | 3133.70; <0.0001 | 0.6885 |
Okuda | 49.45 | 50.21 | 3155.31; <0.0001 | 0.6314 |
CTP | 34.32 | 35.33 | 3170.45; <0.0001 | 0.5287 |
Patients who did not receive transplantation (N=364) | ||||
CLIP | 108.36 | 114.83 | 2793.34; N/A | 0.8519 |
JIS Score | 92.88 | 94.34 | 2811.83; <0.0001 | 0.8328 |
UNOS | 80.40 | 81.58 | 2824.58; <0.0001 | 0.8256 |
BCLC | 70.12 | 70.57 | 2831.59; <0.0001 | 0.7586 |
GRETCH | 67.14 | 68.03 | 2832.14; <0.0001 | 0.7545 |
CUPI | 52.01 | 58.40 | 2841.76; <0.0001 | 0.7057 |
Okuda | 47.90 | 50.44 | 2849.73; <0.0001 | 0.6887 |
CTP | 35.04 | 36.18 | 2863.99; <0.0001 | 0.6610 |
Abbreviations: BCLC: Barcelona Clinic Liver Cancer; CLIP: Cancer of the Liver Italian Program; CTP: Child-Turcotte- Pugh; CUPI: Chinese University Prognostic Index; GRETCH: Group d'Etude et de Traitement du Carcinome Hepatocellulaire; JIS: Japanese Integrated System; UNOS: United Network for Organ Sharing