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. Author manuscript; available in PMC: 2016 Nov 6.
Published in final edited form as: J Vasc Interv Radiol. 2014 Mar 7;25(7):1056–1066. doi: 10.1016/j.jvir.2014.01.010

Table 3. Comparison of HCC Staging Systems.

Staging System Discriminatory Ability Linear Trend X2 Homogeneity Likelihood Ratio X2 Test Akaike Information Criterion; P value of comparison of CLIP to Model Discrimination for Model Validation Cindex
All patients censored to transplantation (N=428)
CLIP 118.18 127.22 2992.80; N/A 0.8503
JIS Score 101.37 103.98 3014.04; <0.0001 0.8474
UNOS 93.14 94.61 3023.41; <0.0001 0.8393
BCLC 79.49 81.97 3032.05; <0.0001 0.7749
GRETCH 72.98 73.40 3038.61; <0.0001 0.7726
CUPI 56.20 64.45 3047.57; <0.0001 0.7037
Okuda 48.99 53.13 3058.89; <0.0001 0.6889
CTP 35.69 38.00 3074.02; <0.0001 0.6445
All patients with intention to treat survival (N=428)
CLIP 154.91 164.43 3057.86; N/A 0.8157
UNOS 136.97 156.90 3073.79; <0.0001 0.7885
JIS Score 130.20 143.95 3080.56; <0.0001 0.7822
BCLC 118.78 133.89 3087.99; <0.0001 0.7761
GRETCH 95.41 111.55 3109.36; <0.0001 0.6927
CUPI 71.06 71.92 3133.70; <0.0001 0.6885
Okuda 49.45 50.21 3155.31; <0.0001 0.6314
CTP 34.32 35.33 3170.45; <0.0001 0.5287
Patients who did not receive transplantation (N=364)
CLIP 108.36 114.83 2793.34; N/A 0.8519
JIS Score 92.88 94.34 2811.83; <0.0001 0.8328
UNOS 80.40 81.58 2824.58; <0.0001 0.8256
BCLC 70.12 70.57 2831.59; <0.0001 0.7586
GRETCH 67.14 68.03 2832.14; <0.0001 0.7545
CUPI 52.01 58.40 2841.76; <0.0001 0.7057
Okuda 47.90 50.44 2849.73; <0.0001 0.6887
CTP 35.04 36.18 2863.99; <0.0001 0.6610

Abbreviations: BCLC: Barcelona Clinic Liver Cancer; CLIP: Cancer of the Liver Italian Program; CTP: Child-Turcotte- Pugh; CUPI: Chinese University Prognostic Index; GRETCH: Group d'Etude et de Traitement du Carcinome Hepatocellulaire; JIS: Japanese Integrated System; UNOS: United Network for Organ Sharing