The Pedigrees for 17 Families with C1S or C1R Mutations
The colored symbols are defined in the key. X denotes individuals with normal result of molecular testing; asterisk (∗) indicates samples included in linkage studies in family 1. Hatch sign (#) indicates individual in family 4 described as “affected” in a previous publication3 but not confirmed by molecular testing. For families 5 (Rahman et al.4), 8 (Hartsfield and Kouseff22), and 11 (Stewart et al.2), a more complete pedigree has been previously published.