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. 2016 Oct 24;2016:4923903. doi: 10.1155/2016/4923903

Table 3.

Association between the expression of WIF1 and β-catenin and clinicopathological parameters of CC (stages IA–IIB).

Variable Cases WIF1 β-Catenin
Number (%) Negative Positive p a Negative Positive p a
Histologic subtype
 Squamous cell carcinoma 172 87.8 133 39 NS 58 114 NS
 Adenocarcinoma 24 12.2 16 8 5 19
FIGO stage
 IA 16 8.2 13 3 NS 6 10 NS
 IB1, IIA1 102 52.0 77 25 31 71
 IB2, IIA2 64 32.7 46 18 25 39
 IIB 14 7.1 13 1 1 13
Tumor grade
 G1 35 19.2 27 8 NS 6 29 NS
 G2/G3 147 80.8 112 35 41 106
Parametrial invasion
 Negative 186 94.9 141 45 NS 62 124 NS
 Positive 10 5.1 8 2 1 9
Surgical margin involved
 No 189 96.4 143 46 NS 63 126 NS
 Yes 7 3.6 6 1 0 7
Lymph node metastasis
 Negative 142 72.4 103 39 NS 51 91 NS
 Positive 54 27.6 46 8 12 42
Tumor size (cm)
 ≤4 117 59.7 90 27 NS 36 81 NS
 >4 79 40.3 59 20 27 52
Cervical stromal invasion
 ≤ one second 86 43.9 56 30 0.002 27 59 NS
 > one second 110 56.1 93 17 34 76
Lymphovascular invasion
 Negative 93 61.6 64 29 0.035 33 60 0.017
 Positive 58 38.4 49 9 10 48
Age (years)
 ≤35∗∗ 35 17.9 30 5 NS 9 26 NS
 >35 161 82.1 119 42 54 107

NS: not significant; HPF: high-power field. aThe p value was determined using the χ 2 test. Significant p values are shown with bold font. The number of patients is less than 196 because of missing data. ∗∗Age (range: 23–66 y, median: 42 y).