Table 3.
Variable | Cases | WIF1 | β-Catenin | |||||
---|---|---|---|---|---|---|---|---|
Number | (%) | Negative | Positive | p a | Negative | Positive | p a | |
Histologic subtype | ||||||||
Squamous cell carcinoma | 172 | 87.8 | 133 | 39 | NS | 58 | 114 | NS |
Adenocarcinoma | 24 | 12.2 | 16 | 8 | 5 | 19 | ||
FIGO stage | ||||||||
IA | 16 | 8.2 | 13 | 3 | NS | 6 | 10 | NS |
IB1, IIA1 | 102 | 52.0 | 77 | 25 | 31 | 71 | ||
IB2, IIA2 | 64 | 32.7 | 46 | 18 | 25 | 39 | ||
IIB | 14 | 7.1 | 13 | 1 | 1 | 13 | ||
Tumor grade∗ | ||||||||
G1 | 35 | 19.2 | 27 | 8 | NS | 6 | 29 | NS |
G2/G3 | 147 | 80.8 | 112 | 35 | 41 | 106 | ||
Parametrial invasion | ||||||||
Negative | 186 | 94.9 | 141 | 45 | NS | 62 | 124 | NS |
Positive | 10 | 5.1 | 8 | 2 | 1 | 9 | ||
Surgical margin involved | ||||||||
No | 189 | 96.4 | 143 | 46 | NS | 63 | 126 | NS |
Yes | 7 | 3.6 | 6 | 1 | 0 | 7 | ||
Lymph node metastasis | ||||||||
Negative | 142 | 72.4 | 103 | 39 | NS | 51 | 91 | NS |
Positive | 54 | 27.6 | 46 | 8 | 12 | 42 | ||
Tumor size (cm) | ||||||||
≤4 | 117 | 59.7 | 90 | 27 | NS | 36 | 81 | NS |
>4 | 79 | 40.3 | 59 | 20 | 27 | 52 | ||
Cervical stromal invasion | ||||||||
≤ one second | 86 | 43.9 | 56 | 30 | 0.002 | 27 | 59 | NS |
> one second | 110 | 56.1 | 93 | 17 | 34 | 76 | ||
Lymphovascular invasion∗ | ||||||||
Negative | 93 | 61.6 | 64 | 29 | 0.035 | 33 | 60 | 0.017 |
Positive | 58 | 38.4 | 49 | 9 | 10 | 48 | ||
Age (years) | ||||||||
≤35∗∗ | 35 | 17.9 | 30 | 5 | NS | 9 | 26 | NS |
>35 | 161 | 82.1 | 119 | 42 | 54 | 107 |
NS: not significant; HPF: high-power field. aThe p value was determined using the χ 2 test. Significant p values are shown with bold font. ∗The number of patients is less than 196 because of missing data. ∗∗Age (range: 23–66 y, median: 42 y).