Table 4.
Variable | 5-year DFSc | 5-year OSc | ||||||
---|---|---|---|---|---|---|---|---|
Univariate | Multivariated | Univariate | Multivariated | |||||
p a | p a | HRb | 95% CI | p a | p a | HRb | 95% CI | |
FIGO stage | ||||||||
IA | <0.001 | NS | 0.002 | NS | ||||
IB1, IIA1 | ||||||||
IB2, IIA2 | ||||||||
IIB | ||||||||
Parametrial invasion | ||||||||
Negative | 0.002 | NS | 0.007 | NS | ||||
Positive | ||||||||
Surgical margin involved | ||||||||
No | 0.008 | NS | 0.036 | NS | ||||
Yes | ||||||||
Lymph node metastasis | ||||||||
Negative | <0.001 | <0.001 | 5.029 | 2.623–9.645 | <0.001 | <0.001 | 5.058 | 2.524–10.137 |
Positive | ||||||||
Tumor size (cm) | ||||||||
≤4 | <0.001 | NS | 0.001 | NS | ||||
>4 | ||||||||
β-Catenin | ||||||||
Negative | 0.001 | 0.035 | 2.588 | 1.071–6.251 | 0.002 | 0.031 | 2.873 | 1.102–7.492 |
Positive |
DFS: disease-free survival; OS: overall survival; HR: hazard ratio; CI: confidence interval; NS: not significant; HPF: high-power field. aSignificant p values are shown in bold font. bHR > 1 indicates that risk for recurrence/death increased; HR < 1 indicates that risk for recurrence/death decreased. cUnivariate and multivariate analyses and Cox proportional hazards regression model. dVariables associated with survival by univariate analysis were adopted as covariates in multivariate analyses.