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. 2016 Oct 24;2016:1564386. doi: 10.1155/2016/1564386

Figure 1.

Figure 1

The signaling pathway of high-fat diet induced IR through TRIM72 and PI3-K/AKT in skeletal muscle. Whether the swimming exercise can improve insulin resistance in Sprague-Dawley rats fed with high-fat diet through inhibiting TRIM72 expression and activating PI3-K/AKT signal pathway should be further testified.