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. 2016 Nov 7;6:36246. doi: 10.1038/srep36246

Table 3. Antibacterial activity of acrolein-containing solutions.

Strains MIC50 (μM)
Reuterin
3-HPA1
Acrolein
None GSH NAC None GSH NAC None GSH NAC
L. innocua 42.6 ± 26.1 2 2 10.1 ± 0.3 2 2 137.0 ± 46.6 2 2
E. coli 34.6 ± 8.5 2 2 13.5 ± 1.7 2 2 61.9 ± 27.0 2 2

Minimum inhibitory concentrations (MIC50s) of acrolein present in reuterin or 3-HPA solution, or of pure acrolein toward two indicator strains in the absence (None) and presence of scavenger compounds glutathione (GSH) and N-acetyl cysteine (NAC). Acrolein was quantified in culture medium after reuterin, 3-HPA and acrolein solutions were supplied. Shown are mean MIC50 of at least three independent experiments.

1IC-PAD investigations showed rapid acrolein formation after addition of 3-HPA solutions to LB medium.

2No inhibition of bacterial growth.