Table 3. Two multiple linear regression models of the determinants of serum 25(OH)D levels in CRC patients.
| Independent | Beta | p value |
|---|---|---|
| Model 1 (n = 115; R = 0.394, R2 = 0.155) | ||
| Age | 0.157 | 0.082 |
| Measurement in summer or autumn (no vs. yes) | 0.311 | 6.8E-4 |
| Body mass index | −0.106 | 0.234 |
| Serrated morphology (no vs. yes) | −0.175 | 0.049 |
| Model 2 (n = 115; R = 0.450, R2 = 0.202) | ||
| Age | 0.142 | 0.106 |
| Measurement in summer or autumn (no vs. yes) | 0.266 | 0.0028 |
| Serrated morphology (no vs. yes) | −0.178 | 0.039 |
| Blood neutrophil count | −0.246 | 0.0051 |
Model 1 included patient age as a basic clinical variable and three other clinicopathological variables with the highest statistical significance in the univariate analyses (BMI, season of measurement, and serrated histology). Model 2 was constructed to test, whether also systemic inflammatory markers had independent predictive value on serum 25(OH)D levels. Serum 25(OH)D, blood neutrophil count, and body mass index were logarithmically transformed because of positive skewness.