Skip to main content
. 2016 Nov 7;6:36687. doi: 10.1038/srep36687

Figure 3. PAI-1 is a direct target of miR-30c.

Figure 3

(A) Schematic representation of the PAI-1 3′ UTR luciferase reporter plasmid. The “seed sequences” and the point mutations in the seed sequences are underlined. (B,C) A miR-30c mimic (30 nmol/L), miR-30c inhibitor (30 nmol/L) or control oligo (30 nmol/L) was co-transfected with the psi-CHECK-2 wild-type or mutated PAI-1 3′ UTR sequence vectors in HEK293 cells. The relative luciferase activity is reported. All data are presented as the mean ±SEM of triplicate independent experiments. *p < 0.05, miR-30c mimic experimental vs. Blank and NC. #p < 0.05, miR-30c inhibitor experimental vs. Blank and NC inhibitor.