Figure 2. Status epilepticus in the NS-Pten HT mice resulted in hyperactivity without changes in anxiety in the elevated plus maze test.

All groups of mice were placed in a 10 minute elevated plus maze test. We first examined (A) overall changes in total distance in the maze and (B) velocity. (C,D) Duration and frequency of visits in the open, center, and closed arms in the maze. Separate video scoring was conducted for the (E,F) frequency and duration of head dips and (G,H) frequency and duration of rearing behavior in the closed arms. Data are shown as mean ± standard error of the mean. *P > 0.05. WT-control n = 18, HT-control n = 12, WT-Seizure n = 15, HT-Seizure n = 14.