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. 2016 Nov 7;6:36661. doi: 10.1038/srep36661

Figure 2. Foxc2 increases fatty acid oxidation in WAT and BAT.

Figure 2

(A) Foxc2 level in iWAT and iBAT after pc-Foxc2 or si-Foxc2 injection for 6 days (n = 6); (B) Palmitate incorporation into different locations of adipose tissues after pc-Foxc2 or si-Foxc2 injection for 6 days (n = 6); (C) Serum TG level of mice after pc-Foxc2 or si-Foxc2 injection for 6 days (n = 10); (D) Serum FFA level of mice after pc-Foxc2 or si-Foxc2 injection for 6 days (n = 10); (E) Relative palmitate oxidation to CO2 in different adipose tissues (n = 6); (F) MC5R and C/EBPβ levels of iWAT after pc-Foxc2 or si-Foxc2 injection for 6 days (n = 6); (G) Protein levels of CPT-1 and phosphorylation level of ACC (the full-length blots of ACC and p-ACC were showed in Figure S6B) in iWAT after pc-Foxc2 or si-Foxc2 injection for 6 days (n = 6); (H) MC5R and C/EBPβ levels of iBAT after pc-Foxc2 or si-Foxc2 injection for 6 days (n = 6); (I) Protein levels of CPT-1 and phosphorylation level of ACC (the full-length blots of ACC and p-ACC were showed in Figure S6B) in iBAT after pc-Foxc2 or si-Foxc2 injection for 6 days (n = 6). pc-Foxc2: adenovirus overexpression vector of Foxc2, si-Foxc2: lentiviral interference vector of Foxc2, CPT-1: carnitine palmitoyl transferase-1, ACC: acetyl-CoA carboxylase, the protein expression was detected by ELISA test. Values are means ± SD. vs. control group, *p < 0.05, **p < 0.01.