Table 2.
Median time to events for included very-early onset (VEO) and non-VEO patients with autosomal dominant polycystic kidney disease. N/A = the median estimate could not be calculated because the failure probability never exceeded 0.5. Hazard ratios and p-values are for unadjusted Cox proportional hazards analysis comparing VEO to non-VEO.
Event | N (%) VEO | Median Age VEO | N (%) Non-VEO | Median Age Non-VEO | Hazard Ratio (95% CI) | P-Value |
---|---|---|---|---|---|---|
Hypertension | 42 (61%) | 20 | 21 (30%) | 38 | 3.15 (1.86–5.34) | <0.0001 |
eGFR ≥140 mL/min/1.73m2 | 19 (38%) | N/A | 24 (48%) | N/A | 1.06 (0.58–1.93) | 0.86 |
eGFR <90 mL/min/1.73m2 | 25 (50%) | 22 | 15 (30%) | 25 | 2.3 (1.08, 3.95) | <0.05 |