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A model of mAb-J reversible self-association illustrating 2 possible morphologies that an associated mAb network could form at high protein concentrations resulting in elevated solution viscosity. On the left, the Fab domain of the antibody is shown in orange and the Fc is green. On the right homology model of mAb-J with protein interfaces of RSA colored in yellow are arranged to show contact points between mAb-J monomers and possible arrangement of associated complexes.
