Figure 10.

Higher magnification images of the paramacular choroid adjacent to CNV (A, C, E, G) and submacular field of choroid (B, D, F, H) in the neovascular AMD demonstrate attenuated choriocapillaris in advance of CNV (C) and a nonlobular pattern of CNV in submacular region (D). Very few IBA1- or HLA-DR⁺-labeled macrophages were ramified in paramacular choroid (E, G) or within the CNV membrane (F, H). There were significantly more HLA-DR⁺ macrophages in the CNV than in the non-CNV region. (B) Merged channels; (C, D) desaturated UEA channel; (E, F) IBA1 channel; (G, H) HLA-DR channel. Scale bar: 25 μm.