Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Nov 1;10:3591–3597. doi: 10.2147/DDDT.S114879

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 Lin et al. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

PMC Copyright notice

Fenretinide controlled hypertension in SHR.

Notes: The WKY (white bars) and SHR (black bars) control groups were administered normal saline, the valsartan-treated SHR group was orally administered 15 mg/kg valsartan twice a day, and the fenretinide-treated SHR group was fed with standard diet supplemented with fenretinide at 737 μmol/kg diet for 1 week (n=8–10 for each group of the rats). Mean blood pressure (A) and systolic blood pressure (B) were measured with a noninvasive tail-cuff method in conscious animals using a computer-assisted detection device. (C) The expressions of PPARγ in the aorta of each group of the rats were tested by Western blots (n=4 for each group). ^*P<0.05; ^**P<0.01; ^***P<0.001 as compared with the indicated groups.

Abbreviations: BP, blood pressure; FEN, fenretinide; PPARγ, peroxisome proliferator-activated receptor gamma; SHR, spontaneously hypertensive rats; WKY, Wistar-Kyoto rats.