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. 2016 Nov 1;24(6):638–649. doi: 10.4062/biomolther.2016.018

Fig. 6.

Fig. 6.

Effect of DW2007 on body weight (A), macroscopic disease (B), colon length (C), colonic myeloperoxidase (MPO) activity (D), and histologic exam (E) in TLR4−/− mice with DSS-induced colitis. DSS, except in the control group, was orally administered to mice treated with saline, DW2007 (AC), or sulfasalazine (SS). Test agents (AC10, 10 mg/kg DW2007; AC20, 20 mg/kg AC; or SS50, 50 mg/kg SS) or saline were orally administered for 3 days after DSS treatment. The mice were killed 18 h after the final administration of test agents. All data are mean ± SD (n=6). #p<0.05 vs. control group. *p<0.05 vs. DSS group.