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Concentration of OVA-specific lgG (left pannel) and lgA (right pannel) at 4 weeks after laser adjuvant (l.a.) and topical application of HA-OVA conjugates with various doses (mean ± SD, n = 4), in comparison to intramuscular (i.m.) injection and transdermal (t.d.) application without laser adjuvants. ***, P < 0.001.
