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. Author manuscript; available in PMC: 2017 Nov 15.
Published in final edited form as: J Immunol. 2016 Oct 14;197(10):3782–3791. doi: 10.4049/jimmunol.1601029

Figure 8.

Figure 8

Effect of PP5 inhibition on GCR signaling and apoptotic response to GC treatment in IL-5 stimulated eosinophils. Eosinophils were incubated in the presence of PP5 specific siRNA or scrambled RNA nonspecific control for 24 h followed by 16 h stimulation with IL-5 and treatment with Dex at the concentration of 1 µM for time dependent assays. A. Effect of PP5 inhibition (top Western blot) on phosphorylation of GCR on Ser-211 in response to 1 h stimulation with Dex. B. Effect of PP5 inhibition of PP5 on apoptosis in IL-5 stimulated cells exposed to Dex. The * p value <0.05 was considered significant by ANOVA. The bars represent the standard error of the mean for n=4.