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(A) Binding site of the orthosomycins, represented by avi (yellow), in D50S, spanning uL16 (cyan), H89 and H91 (gray), and CTC (orange). The additional rRNA and rProteins are colored gray and blue, respectively. (B) Magnification of the binding pocket of avi (yellow) and (C) evn (pink) demonstrating the proximity of CTC domain 2 to the drug’s binding pocket.
