Table 1.

Data collection and refinement statistics

Statistics	D50S–avilamycin	D50S–evernimicin	Avilamycin-free
Crystal information
Space group	I222	I222	P21
a, b, c, Å	170.0, 412.6, 697.9	169.4, 407.4, 692.5	8.1, 34.5, 28.6
α, β, γ, °	90, 90, 90	90, 90, 90	90, 97, 90
Diffraction data statistics
Wavelength, Å	0.873	1.033	0.710
No. of crystals	2	4	1
<I>/<σI>	6.5 (1.01)	9.75 (1.43)	20.7 (3.5)
Resolution, Å	50–3.35 (3.41–3.35)*	30–3.58 (3.64–3.58)	20–1.00 (1.04–1.00)
Observed reflections	1,115,549 (13,797)	982,811 (13,017)	25,930
No. of unique reflections	290,370	263,507(8,630)	14,062
Redundancy	3.8 (3.3)	3.7 (3.4)	5.4 (3.6)
Completeness, %	93.3 (89.2)	94.4 (93.5)	97.5 (99.0)
Refinement statistics
Rwork/Rfree	0.215/0.259	0.206/0.249	0.1089†/0.1197‡
RMSD bonds lengths, Å	0.005	0.008	—
RMSD angles, °	0.991	1.3	—

^*Values in parentheses are for highest-resolution shell.

^†R for all data.

^‡R for data with I > 2σ(I).