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. 2016 Oct 17;113(44):12526–12531. doi: 10.1073/pnas.1604570113

Fig. S3.

Fig. S3.

Effect of deworming on cytokine responses to AscAg, PfRBCs, and PHA. Cytokine concentrations were assessed in supernatants of 72 h-stimulated whole-blood cultures. The estimated effects of albendazole treatment on the production of the significant cytokines over the whole trial period [IL-2 to AscAg (A), TNF (B) and IFN-γ (C) to PfRBCs, and TNF (D) and IL-10 (E) to PHA] are shown (Left). The estimates are calculated based on the differences in treatment versus placebo data but taking into account the clustered design and missing at random. The estimate, beta value is the unit change in cytokine as a result of treatment. (Right) The corresponding geometric means and SE of these cytokine levels [IL-2 to AscAg (F), TNF (G) and IFN-γ (H) to PfRBCs, TNF (I) and IL-10 (J) to PHA] in pg/mL. It should be noted that these geometric means were calculated only in subjects for whom we have data at those follow-up time points. Interpreting these means is valid only under missing completely at random.