TABLE 3.

Primary model results

			Vomiting	Nausea	Total symptom score
Session 1	Slope (daily change)	Group A (Stim on)	−0.40 (95% CI, −0.51 to −0.29); P < .001	−0.33 (95% CI, −0.45 to −0.22); P < .001	−1.30 (95% CI, 01.76 to −0.85); P < .001
		Group B (Stim off)	−0.28 (95% CI, −0.40 to −0.17); P < .001	−0.40 (95% CI, −0.51 to −0.28); P < .001	−1.63 (95% CI, −2.10 to −1.16); P < .001
Session 2	Slope (daily change)	Group A (Stim off)	0.08 (95% CI, −0.08 to 0.23) P < .329	−0.02 (95% CI, −0.18 to 0.14); P < .841	−0.20 (95% CI, −0.83 to 0.42); P < .516
		Group B (Stim on)	−0.04 (95% CI, −0.19 to 0.11); P = .606	0.04 (95% CI, −0.12 to 0.21); P < .585	0.12 (95% CI, −0.51 to 0.75); P < .700
Treatment effect pooled across periods			−0.12 (95% CI, −0.26 to 0.03); P = .116	−0.06 (95% CI, −0.21 to 0.09); P = .431	−0.33 (95% CI, −0.92 to 0.27); P = .277

Model: treatment effect pooled over period, adjusted for age and sex.

Negative values indicate decreases in symptoms.

See Online Appendix Table for additional models with treatment effect by period examinations.

Stim, Stimulation.