Table 2.
Factors of Adverse Outcomes.a
| Variable | Unadjusted Odds Ratio | Adjusted Odds Ratio (95% Confidence Interval) |
|---|---|---|
| Demographics | ||
| Age | 1.04 | 1.05 (1.04-1.06) |
| Recent discharge | 2.33 | 1.97 (1.36-2.83) |
| Diagnostics | ||
| Corrected SIDa | 1.13 | 1.06 (0.72-1.55) |
| Shock Index | 1.38 | 1.63 (1.17-2.25) |
| Hypoxemia | 4.24 | 4.29 (3.07-5.98) |
| CDS first alert activated | ||
| SIRS: HR & RR | 1.85 | 1.56 (1.01-2.42) |
| SIRS: Temp & WBC | 0.21 | 0.42 (0.21-0.86) |
| Sepsis: Perfusion | 0.62 | 0.91 (0.54-1.53) |
| Sepsis: Cardiovascular | 1.96 | 1.51 (0.90-2.51) |
| Sepsis: Renal | 3.50 | 2.80 (1.19-6.61) |
| First alert patient location | ||
| Medicine | 1.72 | 1.67 (1.10-2.53) |
| Critical Care | 3.00 | 3.11 (1.98-4.88) |
Abbreviations: CDS, clinical decision support; HR, heart rate; RR, respiratory rate; SIDa, corrected apparent strong ion difference; SIRS, systemic inflammatory response syndrome; Temp, temperature; WBC, white blood cell count.
Admission cohort months 0 to 12 (N = 1541). Multivariable Logistic Regression model constant = −6.528. Model performance: Nagelkerke R2 = 0.27; Hosmer and Lemeshow test χ2 = 6.90, df = 8, P = .55; C-statistic = 0.81, 95% confidence interval (0.78 to 0.84). Age: one unit increase. Recent Discharge: patient discharged from hospital within 30 days of current hospitalization. Clinical Results: first diagnostics resulted at presentation include SIDa, Shock Index, and Hypoxemia. Patient Location at the patient’s first activated alert includes: Medicine (general medicine, oncology and pulmonary) and Critical Care units (general medicine, intensive nursing care unit, medical cardiac, and medical stroke and cardiac); ICU excluded.