Fig 2. Effect of GRA and GRA derivatives on S. aureus MW2 growth.
Overnight cultures of S. aureus MW2 were adjusted to an OD of 1.0. Then, 100 μl of bacterial culture was inoculated into 5 ml of TSB. The bacterial culture was incubated at 37°C with shaking. When the OD at 660 nm reached 0.3, various concentrations (■: control, ♦: 1/64 MIC, ▲: 1/16 MIC, ●: 1/4 MIC, ×: 1x MIC, +: 2x MIC) of GR-SU or GRA were added to the medium. The growth and colony counts were monitored. Three independent experiments were performed, and the mean ± SD was calculated. The data were analyzed for statistically significant differences compared to untreated control by a two-way ANOVA followed by Dunnett’s post hoc tests. *P<0.05.