Table 1.

Effect of the crude aqueous extract of Thymus serrulatus on the urine volume in mice

Treatment	Cumulative volume of urine (mL)	Urinary excretion (Vo/Vi) ×100	Diuretic action (UEt/UEc)	Diuretic activity (DAt/DAH)
Control NS	4.0±0.51	80	1.0	–
HCTZ 10 mg/kg	6.25±0.86***	125	1.56	1.0
T. serrulatus 125 mg/kg	3.5±0.32	87.5	1.09	0.69
T. serrulatus 250 mg/kg	5.25±0.97*	105	1.31	0.83
T. serrulatus 500 mg/kg	5±0.63*	90	1.12	0.71
T. serrulatus 1,000 mg/kg	5.75±0.84**	115	1.44	0.92

Notes: Cumulative values are expressed as mean ± SEM.

^*P<0.05,

^**P<0.01,

^***P<0.001.

Abbreviations: NS, normal saline; HCTZ, hydrochlorothiazide; SEM, standard error of mean.