Table 5.
Effect of the dichloromethane fraction of aqueous extract of Thymus serrulatus on the electrolyte excretion in mice
| Treatment | Electrolyte concentration (mEq/L)
|
||
|---|---|---|---|
| Na+ | K+ | Na+/K+ | |
| Control NS | 76.2±1.51 | 40.5±1.32 | 1.87 |
| HCTZ 10 mg/kg | 97.9±1.25** | 45.6±1.28* | 2.14 |
| T. serrulatus 125 mg/kg | 68.5±1.40 | 43.7±0.78 | 1.56 |
| T. serrulatus 250 mg/kg | 75.3±1.51 | 40.9±0.85 | 1.84 |
| T. serrulatus 500 mg/kg | 76.3±1.03 | 40.3±1.18 | 1.89 |
| T. serrulatus 1,000 mg/kg | 76.0±1.67 | 41.5±1.33 | 1.83 |
Notes: Cumulative values are expressed as ± mean SEM.
*
P<0.05,
**
P<0.01.
Abbreviations: NS, normal saline; HCTZ, hydrochlorothiazide; SEM, standard error of mean.