Table 6.

Effect of the n-butanol fraction of aqueous extract of Thymus serrulatus on the electrolyte excretion in mice

Treatment	Electrolyte concentration (mEq/L)
	Na+	K+	Na+/K+
Control NS	70.2±1.27	45.5±1.30	1.54
HCTZ 10 mg/kg	113.5±1.48***	53.5±1.42*	2.12
T. serrulatus 125 mg/kg	87.4±1.06**	50.0±1.23*	1.74
T. serrulatus 250 mg/kg	115.2±1.34***	64.9±1.51**	1.77
T. serrulatus 500 mg/kg	92.7±1.16**	58.1±1.01**	1.59
T. serrulatus 1,000 mg/kg	112.8±1.55***	69.4±1.71**	1.62

Notes: Cumulative values are expressed as mean ± SEM.

^*P<0.05,

^**P<0.01,

^***P<0.001.

Abbreviations: NS, normal saline; HCTZ, hydrochlorothiazide; SEM, standard error of mean; X, mean.