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. 2016 Nov 7;11(11):e0166148. doi: 10.1371/journal.pone.0166148

Table 2. Features, interventions, and outcomes of cardiac arrest events.

Variables All patients (n = 678) Targeted temperature management (n = 22) Standard care (n = 656) p-value
Arrest at night, n (%) 419 (61.8) 12 (54.5) 407 (62.0) 0.51
Arrest on weekend, n (%) 201 (29.6) 3 (13.6) 198 (30.2) 0.10
Arrest location, n (%) <0.001
    Intensive care unit 259 (38.2) 0 (0) 259 (39.5)
    General ward 349 (51.5) 6 (27.3) 343 (52.3)
    Emergency department 46 (6.8) 16 (72.7) 30 (4.6)
    Other locations 24 (3.5) 0 (0) 24 (3.7)
Witnessed arrest, n (%) 441 (65.0) 15 (68.2) 426 (64.9) 0.82
Monitored status, n (%) 371 (54.8) 9 (40.9) 362 (55.3) 0.20
Shockable rhythm, n (%) 93 (13.7) 4 (18.2) 89 (13.6) 0.53
Critical care interventions in place at time of arrest, n (%)
  Mechanical ventilation 120 (17.7) 1 (4.5) 119 (18.1) 0.15
  Antiarrhythmics 49 (7.2) 0 (0) 49 (7.5) 0.39
  Vasopressors 245 (36.1) 1 (4.5) 244 (37.2) 0.001
  Dialysis 52 (7.7) 1 (4.5) 51 (7.8) > 0.99
  Pulmonary artery catheter 7 (1.0) 0 (0) 7 (1.1) > 0.99
    Intra-aortic balloon pumping 7 (1.0) 0 (0) 7 (1.1) > 0.99
CPRa duration, min (SDb) 20.3 (19.2) 16.1 (10.6) 20.4 (19.4) 0.72
Body temperature during the first 24 hours after sustained ROSCc
    Fever,d n (%) 173 (25.5) 3 (13.6) 170 (25.9) 0.32
    Highest body temperature, °C (SD) 37.1 (1.6) 36.3 (1.3) 37.2 (1.6) < 0.001
    Lowest body temperature, °C (SD) 35.4 (1.4) 32.1 (1.0) 35.5 (1.3) < 0.001
Percutaneous coronary intervention after sustained ROSC, n (%) 18 (2.7) 2 (9.1) 16 (2.4) 0.11
Withdrawal of life sustaining therapy 0 (0) 0 (0) 0 (0) > 0.99
Survival to hospital discharge, n (%) 144 (21.2) 9 (40.9) 135 (20.6) 0.03
Favourable neurological outcome, n (%) 60 (8.8) 7 (31.8) 53 (8.8) 0.002

aCPR, cardiopulmonary resuscitation

bSD, standard deviation

cROSC, return of spontaneous circulation

dFever was defined as body temperature ≥ 38°C at least once during the first 24 hours after sustained ROSC.