Table 2. Features, interventions, and outcomes of cardiac arrest events.
Variables | All patients (n = 678) | Targeted temperature management (n = 22) | Standard care (n = 656) | p-value |
---|---|---|---|---|
Arrest at night, n (%) | 419 (61.8) | 12 (54.5) | 407 (62.0) | 0.51 |
Arrest on weekend, n (%) | 201 (29.6) | 3 (13.6) | 198 (30.2) | 0.10 |
Arrest location, n (%) | <0.001 | |||
Intensive care unit | 259 (38.2) | 0 (0) | 259 (39.5) | |
General ward | 349 (51.5) | 6 (27.3) | 343 (52.3) | |
Emergency department | 46 (6.8) | 16 (72.7) | 30 (4.6) | |
Other locations | 24 (3.5) | 0 (0) | 24 (3.7) | |
Witnessed arrest, n (%) | 441 (65.0) | 15 (68.2) | 426 (64.9) | 0.82 |
Monitored status, n (%) | 371 (54.8) | 9 (40.9) | 362 (55.3) | 0.20 |
Shockable rhythm, n (%) | 93 (13.7) | 4 (18.2) | 89 (13.6) | 0.53 |
Critical care interventions in place at time of arrest, n (%) | ||||
Mechanical ventilation | 120 (17.7) | 1 (4.5) | 119 (18.1) | 0.15 |
Antiarrhythmics | 49 (7.2) | 0 (0) | 49 (7.5) | 0.39 |
Vasopressors | 245 (36.1) | 1 (4.5) | 244 (37.2) | 0.001 |
Dialysis | 52 (7.7) | 1 (4.5) | 51 (7.8) | > 0.99 |
Pulmonary artery catheter | 7 (1.0) | 0 (0) | 7 (1.1) | > 0.99 |
Intra-aortic balloon pumping | 7 (1.0) | 0 (0) | 7 (1.1) | > 0.99 |
CPRa duration, min (SDb) | 20.3 (19.2) | 16.1 (10.6) | 20.4 (19.4) | 0.72 |
Body temperature during the first 24 hours after sustained ROSCc | ||||
Fever,d n (%) | 173 (25.5) | 3 (13.6) | 170 (25.9) | 0.32 |
Highest body temperature, °C (SD) | 37.1 (1.6) | 36.3 (1.3) | 37.2 (1.6) | < 0.001 |
Lowest body temperature, °C (SD) | 35.4 (1.4) | 32.1 (1.0) | 35.5 (1.3) | < 0.001 |
Percutaneous coronary intervention after sustained ROSC, n (%) | 18 (2.7) | 2 (9.1) | 16 (2.4) | 0.11 |
Withdrawal of life sustaining therapy | 0 (0) | 0 (0) | 0 (0) | > 0.99 |
Survival to hospital discharge, n (%) | 144 (21.2) | 9 (40.9) | 135 (20.6) | 0.03 |
Favourable neurological outcome, n (%) | 60 (8.8) | 7 (31.8) | 53 (8.8) | 0.002 |
aCPR, cardiopulmonary resuscitation
bSD, standard deviation
cROSC, return of spontaneous circulation
dFever was defined as body temperature ≥ 38°C at least once during the first 24 hours after sustained ROSC.