Table 1. Summary of muscle contractile properties.
| Muscle | Parameter | WT ± SEM | n (Animals) | R6/2 ± SEM | n (Animals) | p value |
|---|---|---|---|---|---|---|
| EDL | Weight | 12.11 ± 1.09 mg | 15 (duplicate) | 6.67 ± 0.36 mg | 10 (duplicate) | < 0.001 |
| CSA | 2.25 ± 0.10 mm2 | 15 (duplicate) | 2.84 ± 0.11 mm2 | 10 (duplicate) | < 0.001 | |
| Specific Force (Twitch) | 1.88 ± 0.53 mN/ mm2 | 15 (duplicate) | 7.67 ± 1.18 mN/ mm2 | 10 (duplicate) | < 0.001 | |
| Specific Force (Tetanus) | 24.18 ± 3.50 mN/mm2 | 14 (single) | 59.63 ± 10.82 mN/mm2 | 5 (single) | 0.02 | |
| SOL | Weight | 6.27 ± 0.29 mg | 15 (duplicate) | 8.00 ± 0.52 mg | 10 (duplicate) | 0.01 |
| CSA | 2.49 ± 0.05 mm² | 15 (duplicate) | 2.72 ± 0.09 mm² | 10 (duplicate) | 0.04 | |
| Specific Force (Twitch) | 0.92 ± 0.08 mN/mm2 | 15 (duplicate) | 1.35 ± 0.38 mN/mm2 | 10 (duplicate) | 0.29 | |
| Specific Force (Tetanus) | 39.38 ± 3.19 mN/ mm2 | 15 (single) | 41.41 ± 6.41 mN/ mm2 | 7 (single) | 0.78 |
Values are reported as mean ± SEM. n is the number of animals. Single twitch measurements are in duplicates (left and right muscle of each animal), tetanus measurements as single muscle. CSA: cross sectional area.