. Author manuscript; available in PMC: 2017 Oct 11.

Published in final edited form as: J Am Coll Cardiol. 2016 Oct 11;68(15):1609–1617. doi: 10.1016/j.jacc.2016.07.745

Table 1.

Total mortality from randomization in the Trials of Hypertension Prevention through 2013 by sodium intervention group.

	Randomized Intervention
	Sodium Reduction	Usual Care
A. Deaths/ Total (%)
TOHP I	33/327 (10.1)	44/417 (10.6)
TOHP II	82/1191 (6.9)	92/1191 (7.7)
B. Hazard Ratios*	HR	95% CI	p
Model 1
TOHP I	0.84	0.54-1.32	0.46
TOHP II	0.85	0.63-1.14	0.28
Combined	0.85	0.66-1.09	0.19
Model 2
TOHP I	0.86	0.54-1.37	0.52
TOHP II	0.85	0.63-1.15	0.30
Combined	0.85	0.66-1.10	0.21

From Cox regression analysis stratified by trial and adjusted for clinic, age, race, sex, and weight loss intervention (Model 1); plus baseline weight and sodium (Model 2).

HR = hazard ratio; CI = confidence interval.