Figure 1.

Push-pull organization of excitation and inhibition in the receptive fields of relay cells in carnivore and rodent. a, Anatomical reconstruction of a feline Off-center shown above membrane currents evoked by dark and bright discs flashed in the center (left) and annuli flashed in the surround of the receptive field (right). Each panel represents two individual responses to the stimulus, with averaged responses to multiple stimulus trials (bold traces) shown below at 2× gain. Icons at left represent stimuli. Black represents responses to dark stimuli. Gray represents responses to bright stimuli. Pale gray lines indicate baseline. Dark gray bars represent stimulus duration. b, c, Equivalent format as in a but for an Off-center cell in rat (b) and an On-center relay in mouse (c).