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. 2016 Oct 1;23(10):1212–1221. doi: 10.5551/jat.32680

Table 3. Correlations of the positive ratios of cells expressing proinflammatory/anti-inflammatory cytokines in carotid plaque with glucose metabolism or proinflammatory/anti-inflammatory properties of circulating monocytes.

Percent of positive cells in plaque
TNF-α
IL-6
IL-10
ρ P-value ρ P-value ρ P-value
FPG 0.191 0.371 0.346 0.098 −0.471 0.020
IRI −0.066 0.759 −0.030 0.891 −0.543 0.006
HbA1c 0.246 0.247 0.466 0.022 −0.428 0.037
HOMA-IR −0.014 0.947 0.087 0.686 −0.640 <0.001*
mRNA level in monocytes
    TNF-α 0.444 0.034 0.406 0.054 0.212 0.330
    IL-6 0.309 0.142 0.148 0.491 −0.130 0.544
    IL-10 −0.251 0.248 −0.362 0.090 0.145 0.508

FPG, fasting plasma glucose; IRI, immunoreactive insulin; HbA1c, hemoglobin A1c; HOMA-IR, homeostasis model assessment of insulin resistance.

*

P < = 0.0008.

ρ, Spearman's rank correlation coefficient