Table 4. Correlations between the expression levels of proinflammatory/anti-inflammatory cytokines in carotid plaque and glucose metabolism or proinflammatory/anti-inflammatory phenotypes of circulating monocytes.
mRNA level in plaque |
||||||
---|---|---|---|---|---|---|
TNF-α |
IL-6 |
IL-10 |
||||
ρ | P-value | ρ | P-value | ρ | P-value | |
FPG | 0.185 | 0.399 | 0.219 | 0.304 | 0.259 | 0.222 |
IRI | −0.041 | 0.854 | −0.256 | 0.228 | 0.241 | 0.256 |
HbA1c | 0.527 | 0.010 | 0.359 | 0.085 | 0.101 | 0.640 |
HOMA-IR | −0.027 | 0.904 | −0.110 | 0.607 | 0.238 | 0.264 |
mRNA level in monocytes | ||||||
TNF-α | 0.459 | 0.027 | 0.332 | 0.122 | −0.053 | 0.809 |
IL-6 | 0.091 | 0.680 | 0.427 | 0.037 | −0.102 | 0.636 |
IL-10 | −0.360 | 0.100 | −0.322 | 0.134 | −0.091 | 0.678 |
FPG, fasting plasma glucose; IRI, immunoreactive insulin; HbA1c, hemoglobin A1c; HOMA-IR, homeostasis model assessment of insulin resistance. ρ, Spearman's rank correlation coefficients