Table 1.
The chemical components and molar ratios of liposomes in this study
| Liposome | Lipid components | Molar ratio | Loaded with calcein |
|---|---|---|---|
| 4%PEG-HS-Chol | HSPC/Chol/DSPE-PEG2000/DSPE-DTPA | 57:38:4:1 | No |
| 1%PEG-HS-CHEM | HSPC/CHEM/DSPE-PEG2000/DSPE-DTPA | 57:41:1:1 | No |
| 2%PEG-HS-CHEM | HSPC/CHEM/DSPE-PEG2000/DSPE-DTPA | 57:40:2:1 | No |
| 4%PEG-HS-CHEM | HSPC/CHEM/DSPE-PEG2000/DSPE-DTPA | 57:38:4:1 | No |
| 4%PEG-HS-Chol-Cal | HSPC/Chol/DSPE-PEG2000/DSPE-DTPA | 57:38:4:1 | Yes |
| 1%PEG-HS-CHEM-Cal | HSPC/CHEM/DSPE-PEG2000/DSPE-DTPA | 57:41:1:1 | Yes |
| 2%PEG-HS-CHEM-Cal | HSPC/CHEM/DSPE-PEG2000/DSPE-DTPA | 57:40:2:1 | Yes |
| 4%PEG-HS-CHEM-Cal | HSPC/CHEM/DSPE-PEG2000/DSPE-DTPA | 57:38:4:1 | Yes |
Abbreviations: PEG, polyethylene glycol; HSPC, hydrogenated soy phosphatidylcholine; Chol, cholesterol; DSPE-PEG2000, PEG2000 conjugated distearoyl phosphatidylethanolamine; DSPE-DTPA, diethylenetriaminepentaacetic acid-derivatized DSPE; CHEM, cholesteryl hemisuccinate; Cal, calcein.