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Interleukin-37 (IL-37) suppressed tube formation in human umbilical vein endothelial cells (HUVECs). (A) Representative pictures of control and recombinant human IL-37 (rhIL-37) pretreatments. (B) Quantitative analysis of tube formation. Results are expressed relative to the control. (C) Supernatant vascular endothelial growth factor level from HUVECs pretreated with rhIL-37 or control. **P < 0.01; n=3.
