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Age at diagnosis and pathology characteristics of BRCA1/BRCA2 mutation carriers
| BRCA1/2+ (n=18) | BRCA1/2 VUS (n=15) | Non-BRCA1/2 (n=199) | |
|---|---|---|---|
| Age (years), mean (range) | 49.5 (40–75) | 64.8 (41–84) | 66.1 (28–89) |
| BRCA1, n (%) | 12 (67) | 3 (20) | N/A |
| BRCA2, n (%) | 6 (33) | 12 (80) | N/A |
| Pathology, n | |||
| High-grade serous | 15 | 11 | 166 |
| Endometrioid | 1 | 4 | 15 |
| Adenocarcinoma | 2 | 0 | 13 |
| Mixed types | 0 | 0 | 5 |
| Stage, n | |||
| I | 4 | 5 | 25 |
| II | 0 | 0 | 6 |
| III | 12 | 9 | 112 |
| IV | 2 | 1 | 39 |
| Not classified | 0 | 0 | 15 |
VUS, variants of unknown significance.
