Table 3. Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 polymorphisms with the serum TXB2 concentration in ischemic stroke patients.
| SNP | TXB2 concentration (pg/mL) | P-value |
|---|---|---|
| MDR1 (rs1045642) | ||
| TT | 18.44±22.54 | 0.015a |
| TC+CC | 138.50±217.86 | |
| TBXA2R (rs1131882) | ||
| CC | 234.59±449.53 | 0.037a |
| CT+TT | 73.77±138.77 | |
| PLA2G7 (rs1051931–rs7756935) | ||
| AA-CC carriers | 68.91±67.05 | 0.750 |
| AA-CC noncarriers | 122.71±290.30 | |
| PEAR1 (rs12041331–rs1256888) | ||
| AA-GG carriers | 54.60±88.31 | 0.223 |
| AG-GG noncarriers | 87.29±216.19 |
a After Benjamini-Hochberg false discovery rate correction, P>0.05.