Table 4. Associations of MDR1, TBXA2R, PLA2G7, and PEAR1 polymorphisms with the maximal ADP-induced aggregation in ischemic stroke patients.
SNP | ADP-induced aggregation | P-value |
---|---|---|
MDR1 (rs1045642) | ||
TT | 33.60±16.61 | <0.001 |
TC+CC | 44.73±15.96 | |
TBXA2R (rs1131882) | ||
CC | 45.77±12.88 | 0.048a |
CT+TT | 40.34±14.33 | |
PLA2G7 (rs1051931–rs7756935) | ||
AA-CC carriers | 57.68±13.83 | 0.022 |
AA-CC noncarriers | 43.33±15.10 | |
PEAR1 (rs12041331–rs1256888) | ||
AA-GG carriers | 49.04±17.05 | 0.377 |
AG-GG noncarriers | 42.79±14.80 |
aAfter Benjamini-Hochberg false discovery rate correction, P>0.05.