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. 2016 Sep 19;37(11):1442–1448. doi: 10.1038/aps.2016.90

Table 6. Associations of MDR1, TBXA2R, PLA2G7 and PEAR1 polymorphisms with aspirin resistance in ischemic stroke patients.

SNP n (%) Aspirin insensitive (n=33) Aspirin sensitive (n=250) P-value OR 95% CI
MDR1 (rs1045642)          
TT 2 (6.1) 59 (23.6) 0.021 0.421 0.233–0.759
TC+CC 31 (93.9) 191 (76.4)      
TBXA2R (rs1131882)          
CC 27 (81.8) 156 (62.4) 0.028 2.712 1.080–6.810
CT+TT 6 (18.2) 94 (37.6)      
PLA2G7 (rs1051931–rs7756935)          
AA-CC carriers 3 (9.1) 3 (1.2) 0.023 8.233 1.590–42.638
AA-CC noncarriers 30 (90.9) 247 (98.8)      
PEAR1 (rs12041331–rs1256888)          
AA-GG carriers 6 (18.2) 63 (25.2) 0.378 0.660 0.260–1.671
AG-GG noncarriers 27 (81.8) 187 (74.8)