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. 2016 Oct 25;2016:3475356. doi: 10.1155/2016/3475356

Table 5.

Effects of HEAS on MPO and SOD activity and on GSH and LOOH levels in colon tissue of DSS-induced colitic mice.

Treatment Dose
(mg/kg, p.o)
MPO (mD.O/mg of protein) SOD
(U/mg of tissue)
GSH
(µg/mg of tissue)
LOOH (mmol/mg of tissue)
Non-colitic Vehicle 1.15 ± 0.50 1.36 ± 0.22 797.50 ± 111.10 2.03 ± 0.58
Colitic Vehicle 4.24 ± 0.71a 0.15 ± 0.03a 454.70 ± 78.24a 3.99 ± 0.60a
Colitic 5-ASA 100 3.80 ± 0.24a 1.10 ± 0.10b 424.78 ± 59.28a 4.02 ± 0.29a
Colitic HEAS 10 2.96 ± 0.11a,b 1.35 ± 0.04b 444.12 ± 18.42a 3.52 ± 0.42a
Colitic HEAS 100 1.26 ± 0.36b 1.36 ± 0.64b 482.70 ± 62.52a 4.14 ± 0.34a

a P < 0.001 versus non-colitic vehicle group, b P < 0.01 versus colitic vehicle group.