Table 1.
Characteristics of resected stage 1 and 2 hepatocellular cancer patients: Honolulu, Tokyo and Shanghai
| Characteristic | Honolulu (n = 146) n (%) | Tokyo (n = 250) n (%) | Shanghai (n = 177) n (%) | P value |
| Mean age in years | 62.7 (SD 11.4) | 67.0 (SD 8.7) | 50.6 (SD11.1) | < 0.0001 |
| Age < 50 yr | 18 (12.3) | 8 (3.2) | 83 (46.9) | < 0.0001 |
| Males | 100 (68.5) | 180 (72.0) | 145 (81.9) | 0.01 |
| Hepatitis B positive | 62 (42.5) | 35 (14.3) | 167 (94.4) | < 0.0001 |
| Hepatitis C positive | 39 (26.7) | 163 (66.8) | 5 (3.3) | < 0.0001 |
| Hepatitis B and C positive | 5 (3.4) | 4 (1.6) | 3 (2.0) | 0.50 |
| Stage 1 | 129 (88.4) | 68 (27.2) | 91 (51.4) | < 0.0001 |
| Childs A | 143 (99.3) | 224 (89.6) | 172 (97.2) | < 0.0001 |
| Cirrhosis | 60 (41.1) | 133 (56.8) | 163 (92.6) | < 0.0001 |
| Mean tumor size (cm) | 6.4 (SD 4.6) | 3.0 (SD 2.1) | 3.9 (SD 2.6) | < 0.0001 |
| Tumor size < 5.0 cm | 75 (51.4) | 213 (85.2) | 137 (77.4) | < 0.0001 |
| AFP < 20 ng/mL | 72 (49.3) | 144 (57.6) | 70 (39.6) | 0.0011 |
| Albumin < 3.5 g/dL | 23 (15.8) | 85 (34) | 21 (11.9) | < 0.0001 |
Hepatitis B surface (n = 6); hepatitis C virus (n = 32); Child-Pugh (n = 2); cirrhosis (n = 17); albumin n = 17). AFP: Alpha fetal protein.