Table 2.
Univariable and multivariable Cox regression to assess potential risk factors for BK polyomavirus nephropathy
| Crude HR (+) BKVN | 95%CI | P value | Adjusted HR (+) BKVN | 95%CI | P value | |
| Gender (female) | 0.66 | 0.16-2.66 | NS | |||
| Ethnicity (reference: European) | ||||||
| Asian | 6.36 | 1.06-38.16 | 0.043 | 3.731 | 0.61-22.92 | 0.154 |
| Māori/Pacific Islander | 4.75 | 0.87-25.94 | 0.072 | 2.631 | 0.45-15.25 | 0.279 |
| Co-morbidity | ||||||
| Diabetes mellitus | 2.06 | 0.42-9.94 | NS | |||
| Basiliximab induction | 0.75 | 0.18-3.03 | NS | |||
| Tacrolimus | 1.64 | 0.44-6.11 | NS | |||
| Thymoglobulin for rejection | 0.03 | 0.00-88.65 | NS | |||
| Cold ischaemia time | 1.18 | 1.06-1.32 | 0.003 | 1.181 | 1.04-1.35 | 0.009 |
| Acute rejection (≥ 1 episode)2 | 3.72 | 0.93-14.91 | 0.063 | 4.051 | 0.99-16.53 | 0.051 |
| HLA mismatch | 1.15 | 0.75-1.77 | NS |
1
Variables included in the multivariable Cox regression model;
2
Acute rejection at any time point. HR: Hazard ratio; CI: Confidence interval; (+) BKVN: BK polyomavirus nephropathy nephropathy; HLA: Human leukocyte antigen; NS: No significance.