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. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Top Curr Chem (Cham). 2016 May 30;374(3):35. doi: 10.1007/s41061-016-0028-0

Scheme 6.

Scheme 6

Alcohol-mediated hydrohydroxyalkylation of allenes.a

aYields are of material isolated by flash chromatography on silica gel. Diastereoselectivity was determined through 1H NMR analysis of crude reaction mixtures. dippf = bis-(diisopropylphosphino)ferrocene