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. 2016 Nov 8;6:36662. doi: 10.1038/srep36662

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(a) Trabecular bone microarchitecture by 3D micro-CT analysis in the proximal tibial metaphysis. Trabecular bone was analysed by micro-CT in sham-operated or ovariectomized mice after vehicle, E2 (50 ng/kg) or NC treatment (3 and 6 mg/kg). (b) Bone volume/tissue volume (BV/TV), trabecular space (Tb. Sp), trabecular thickness (Tb. Th) and trabecular number (Tb. N). Values are means ± SE from 6 mice per group. (*p < 0.05 vs. control).