Table 3. The list of 17 AF top SNPs. It includes four independent SNPs at the PITX2 locus (with a number in parenthesis), and one top SNP at remaining 13 AF loci.

AF SNP	Closest Gene	Locus	Coding allele	Non-coding allele	Coding allele frequency	Source
rs6666258	KCNN3	1q21.3	C	G	0.3	13
rs3903239	PRRX1	1q24.2	G	A	0.45	9
rs4642101	CAND2	3p25.1	T	G	0.28	10
rs1448818	PITX2 (2)	4q25	C	A	0.17	14
rs6817105	PITX2 (1)	4q25	C	T	0.12	9,11
rs4400058	PITX2 (3)	4q25	A	G	0.12	14
rs6838973	PITX2 (4)	4q25	T	C	0.47	14
rs13216675	GJA1	6q22.31	C	T	0.27	10
rs3807989	CAV1	7q31.2	A	G	0.44	9
rs10821415	C9orf3	9q22.32	A	C	0.40	9
rs12415501	NEURL	10p14	T	C	0.11	10
rs10824026	SYNPO2L	10q22.2	G	A	0.14	9
rs6490029	CUX2	12q24.11	A	G	0.23	10
rs10507248	TBX5	12q24.21	G	T	0.23	10
rs1152591	SYNE2	14q23.2	A	G	0.45	9
rs7164883	HCN4	15q24.1	G	A	0.09	9
rs2106261	ZFHX3	16q22.3	T	C	0.16	9,12